People
Primary Investigator
Matthew Soellner, PhD.
Roush Assistant Professor of Chemistry
Professor Soellner's fervor lies in the intricate realm of drug targeting within the kinome. His illustrious career has been interwoven with the academic tapestry of the University of Michigan, where he has made an indelible mark over the years. He boasts a multifaceted background, having lent his expertise to the medical school's department of Internal Medicine, the College of Pharmacy, and currently, the LSA’s Chemistry department – where he currently has a teaching appointment for Organic chemistry (CHEM210).
Beyond the scholarly pursuits of organic chemistry, medicinal chemistry, and chemical biology, Professor Soellner finds solace in the embrace of his loved ones during holidays and vacations. He embarks on awe-inspiring journeys alongside his family, exploring the enchanting landscapes of numerous national parks and state parks that span the length and breadth of the country. This parallel passion for nature's beauty echoes the depth of his scientific curiosity and contributes to the vibrant mosaic of his persona.
Post-Doctoral Researchers
Wuxiang Mao, PhD.
Wuxiang was a post-doctoral researcher in the Soellner Lab from Wuhan, China. As an unwavering synthetic chemist, he tirelessly crafts an array of small-molecule inhibitors meticulously tailored for tyrosine kinases, displaying his unwavering dedication to advancing scientific understanding.
Beyond the laboratory's confines, Wuxiang cherishes moments spent with his beloved wife and two cherished children, a testament to his devotion to both his scientific pursuits and his family life. Moreover, his vibrant personality shines through his exceptional sense of humor, infusing the lab with a refreshing and uplifting energy that invigorates the entire team.
Sultan Ahmed, PhD.
Sultan is a post-doctoral research in the Soellner lab from New York state. He received his PhD from Stony Brook University under the guidance of Dr. Todd Miler where he fostered his love for kinases! In the Soellner lab, he is currently involved in projects revolving around the Alk-kinase and its involvement in non small cell lung cancer (NSCLC).
In his free time, he enjoys weight-lifting, petting cats, PC-gaming and rock climbing!
Lab Manager
Nathalie Vandecan
Nathalie attained her bachelor's degree from Université Catholique de Louvain. Nathalie has achieved a remarkable level of proficiency in maintaining a harmonious equilibrium within her extensive poultry collection. She draws insightful parallels between the melodious symphony of clucks and the intricate patterns that underlie scientific revelations.
In addition to cultivating an environment of serenity within the chicken coops, Nathalie seamlessly applies the nuances of their distinctive pecking order to the dynamics of our laboratory. This application of her poultry management expertise imbues the concept of effective leadership with a novel significance.
Infused with a discerning wit, Nathalie cultivates an ambiance of levity and vibrancy within the laboratory. She firmly subscribes to the belief that humor constitutes an enigmatic catalyst for augmenting both creativity and camaraderie. Nathalie approaches her laboratory projects with the same fervor she invests in her poultry curation, as well as her pursuit of emerging culinary trends. The interconnection between ostensibly disparate passions frequently culminates in unanticipated breakthroughs and pioneering solutions within the laboratory setting.
Graduate Students
Annika Tharp
Chemistry; Organic Cluster
Annika, a native of Ann Arbor, embarked on her academic journey at Indiana University, where she pursued her undergraduate studies and obtained a Bachelor of Science degree in Chemistry. Currently, she is a diligent and aspiring fourth-year Chemistry PhD student, conducting her research in the Soellner lab.
Her research endeavors focus on the synthesis of a diverse range of kinase inhibitors, with the ultimate aim of enhancing the efficacy of existing cancer therapeutics, thereby advancing the state-of-the-art treatment modalities for this devastating disease.
Beyond her rigorous work in the laboratory, Annika embraces a multifaceted lifestyle. She indulges her passion for figure skating, gracefully gliding across the ice in pursuit of both physical and artistic expression. In her leisure time, she finds solace in the meditative art of crocheting, engaging in mind-stimulating puzzles, and delving into captivating literary works. Additionally, Annika thrives on exploring new horizons, embarking on adventures that allow her to discover the world's wonders. Moreover, she appreciates the delicate artistry and culinary delights of sushi, savoring the intricacies of this traditional Japanese cuisine.
Annika's academic pursuits, along with her diverse range of hobbies and interests, illustrate her well-rounded nature and passion for both intellectual growth and personal fulfillment.
Christopher Bingham
Chemistry; Chemical Biology Cluster
Christopher (Chris) earned his Bachelor of Science degree in Chemical Biology from the University of California, Berkeley (Cal). During his time at Cal, he actively participated in various laboratory settings, including the Pavement Research Center and a computational chemistry group. He applied density functional theory to simulate nano-assembly of bis(imino)pyridine ligands, expanding his skill set in computational simulations. After graduation, Chris worked as a clinical laboratory scientist at Sutter Health Memorial Medical Center in Modesto, California, conducting testing on patient samples.
Currently, Chris is deeply involved in a multifaceted research project on the conformational regulation of Src through allostery. He is also optimizing a biochemical global conformation assay, focusing on incorporating full-length Src. These endeavors highlight his dedication to advancing our understanding of complex biochemical processes.
Outside the lab, Chris enjoys traveling, playing the piano, cooking, building computers, and spending time with his two long-haired cats.
Jennalise Ellis
Chemistry; Chemical Biology Cluster
Jennalise (Jenna) pursued her academic journey at Kalamazoo College after spending her early years in metropolitan Detroit. There, she earned a Bachelor of Arts degree in Chemistry and German, focusing on natural product synthesis.
To gain practical experience, Jenna participated in summer chemistry internships at renowned institutions such as Wayne State University, Friedrich-Alexander University in Germany, and Bridge Organics. These internships expanded her knowledge in medicinal, inorganic, and organic chemistry.
Driven by her passion for chemical biology and protein kinases, Jenna joined the Soellner lab. Currently, her research focuses on bivalent inhibition of Abl kinase and the development of an allosteric inhibitor for Src kinase. She aims to contribute to the understanding of chemical biology in protein kinases and explore potential therapeutic opportunities.
Beyond her scientific pursuits, Jenna finds joy in spending time with her beloved canine companion, Rigby. She also engages in board games, gardening, and ambitious DIY home renovation projects.
Furyal Ahmed
Biophysics
Furyal Ahmed is presently pursuing her doctoral studies in the Biophysics program at the University of Michigan. She completed her undergraduate education at Agnes Scott College, where she obtained a Bachelor of Science degree in Biochemistry and Molecular Biology. Furyal's research pursuits revolve around investigating the intricate relationship between protein structure and function, particularly in the context of disease pathology. Currently, her primary focus lies in the development of innovative methodologies to screen and identify inhibitors of protein-protein interactions. By employing her expertise in biophysics, Furyal aims to contribute to the advancement of therapeutic interventions for various diseases.
Outside of her academic endeavors, Furyal finds solace in culinary exploration, experimenting with new recipes to broaden her cooking repertoire. Additionally, she nurtures her artistic inclinations through activities such as knitting and honing her painting skills.
Rajanti Dey
Chemistry; Chemical Biology Cluster
Rajanti pursued her undergraduate studies at the esteemed Indian Institute of Science in India, where she focused on Chemistry as her major and Biology as her minor. Presently, she is actively engaged in a significant project centered around the ancestral backtracking of Abl-tyrosine kinase enzymes. Her primary objective is to acquire a comprehensive mechanistic understanding of Abl's discernment concerning specific cancer drugs, particularly in relation to their shared ancestors with other kinase families.
Beyond her professional endeavors, Rajanti possesses a deep passion for traveling and indulges in the culinary arts, relishing the experience on most occasions. Interestingly, despite growing up in the tropical heat of India, she has developed an affinity for Michigan's winter climate, as her thermoreceptors have surprisingly adapted to its colder temperatures (excluding the challenges posed by snow/ice storms and power outages lasting for prolonged periods).
Pui Ki Tsang
Chemistry; Chemical Biology Cluster
Pui Ki received her Bachelors of Science in Biochemistry from Stony Brook University, where her research primarily revolved around developing mechanisms to modulate kinase conformations. This involved working with biosensor plasmids using the Flexi Cloning system technique and delving into protein-protein interactions through single molecule microscopy.
Outside of her academic pursuits, Pui Ki indulges in traveling, culinary experiences, and cherising moments with her three cats and family. An interesting fact about her is that she became a new mother in September 2023!
Diana Nichols
Chemistry; Organic Cluster
Diana received her Bachelors of Science in Chemistry (ACS certified) with a minor in philosophy from the University of Michigan-Dearborn. There, her research focused on the synthesis and characterization of B2-vitamin derivatives with applications in vitamin deficiency detection.
Diana is an avid collector of vintage vinyl records, boasting a collection of over 500 albums!
Laurelee Boon
Chemistry; Organic Cluster
Laurelee received her bachelor of science in Chemistry, from Knox College in Galesburg, Illinois. While there, she worked on synthesizing Lesquerella derived biophosphonates! In the Soellner lab, she is interested in the interface of organic synthesis with medicinal chemistry and biological applications.
When not in the lab, Laurelee enjoys crocheting and baking (although she has set her oven on fire twice...), as well as outdoor activities like hiking and exploring the outdoors!
Rotation Students
No Current Rotators :) If interested, e-mail soellner@umich.edu.
Undergraduate Students
Evelyn Peterson
Chemistry Major, Art Minor
Evelyn is a dedicated undergraduate student, currently pursuing a major in Chemistry with a minor in Art History. Her academic pursuits showcase her diverse interests and commitment to both the sciences and humanities. Notably, she has been actively engaged in collaborative work with Christopher, focusing on protein expression and purification, which underscores her practical laboratory experience and scientific proficiency.
Beyond her academic pursuits, Evelyn actively participates in campus organizations and extracurricular activities. She is an enthusiastic member of the Sierra Club, where she channels her passion for environmental sustainability and contributes to initiatives promoting ecological awareness. Additionally, Evelyn showcases her artistic side as a member of a student-run dance company, leveraging her talent and love for dance to create captivating performances.
Evelyn's involvement in these varied pursuits reflects her multidimensional nature and her desire to engage in meaningful endeavors both inside and outside of the classroom. Her dedication to her studies, research, and extracurricular activities exemplifies her commitment to personal growth and making a positive impact in her academic and social spheres.
Chyenne Igunbor
Biochemistry Major
Chyenne Igunbor is a driven and accomplished undergraduate student, currently in the class of 2025, pursuing a major in Biochemistry. With a year of experience working in the laboratory, she has demonstrated her commitment to scientific research and its practical applications. As a first-generation college student, Chyenne has exhibited exceptional determination and resilience in her academic journey.
Recognized for her academic excellence, Chyenne was awarded the prestigious May-Walt Summer Research Scholarship, which further attests to her dedication and potential in the field. Hailing from the picturesque region of northern Michigan, she has cultivated a deep appreciation for her surroundings and draws inspiration from its natural beauty.
Chyenne's aspiration lies in the medical field, where she aims to make a meaningful impact in the lives of others. Her passion for healthcare and patient well-being drives her pursuit of a future career in medicine. In her leisure time, she indulges in the delights of sushi and finds solace in a refreshing Diet Coke, enjoying these simple pleasures as a means to recharge and find balance in her demanding schedule.
Brian Cavanaugh
Biochemistry Major, History Minor
Brian is currently a sophomore pursuing a major in Biochemistry, with a minor in History. They are engaged in collaborative efforts with Chris, actively acquainting themselves with the laboratory environment and contributing to a range of tasks encompassing protein purification, expression, and assay work.
Their professional aspirations include a commitment to further education, with the intent of pursuing graduate studies leading to the attainment of a Ph.D. in Biochemistry or a closely related discipline. Their long-term career objective centers on securing a position within the pharmaceutical industry, wherein they can apply their expertise to aid in the development of life-saving medications.
Beyond their academic undertakings, Brian exhibits a profound enthusiasm for sports, with a particular affinity for Michigan sports and professional leagues, particularly baseball (rooting for the Red Sox) and football. In their leisure hours, sports engagement is a prevailing interest. Additionally, they possess a fervor for golf and frequently engage in recreational activities such as pickleball and board games with their social circle. Notably, it is intriguing to mention that they are a twin, which adds a unique facet to their personal background.
Jack Hammett
Chemistry Major, Philisophy Minor
Jack is a dedicated scholar pursuing a Bachelor's degree in Chemistry with a minor in philosophy. Currently, he is engaged in collaborative research with Annika, with his focus lying within the realm of chlorination and other facets pertinent to kinase inhibitor synthesis and mechanistic studies.
Beyond the academic sphere, Jack exhibits a multifaceted persona. He is the captain of the sailing team -- wherein the team competes competitively around the country during weekends in the fall and spring. Additionally, he has a fervent passion for New Orleans sports, particularly the revered New Orleans Saints football team.